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KMID : 0362919920100020219
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Journal of the Korean Society for Therapeutic Radiology and Oncology
1992 Volume.10 No. 2 p.219 ~ p.225
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The Results of Curative Radiation Therapy for 49 Patients of the Uterine Cervical Carcinomas
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Ryu Mi-Ryeong
Kim Yeon-Sil
Choi Byung-Ock
Yoon Sei-Chul
Shinn Kyung-Sub
Namkoong Sung-Eun
Kim Seung-Jo
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Abstract
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Fifty patients with carcinoma of the uterine cervix received curative radiotherapy by external irradiation of the whole pelvis and intracavitary radiation at the Department of Therapeutic Radiology, Kangnam St. Mary´s Hospital from September,1983 to October, 1986. External beam whole pelvic irradiation was done first up to 4500-5940 cGy in 5 weeks to 6.5 weeks, followed by an intracavitary radiation. Total dose of radiation to point A varied from 6500 cGy to l1344 cGy (average 6764 cGy).
Of the 50 patients, one patient was lost to follow up and follow up period of the remaining 49 patients ranged from 3 months to 93 months (median 32 months). According to FIGO classification, 6 (12.2%) were in stage Ⅰb, 6(12.2%) in stage Ⅰa, 25 (51%) in stage Ⅱb, 7 (14%,) in stage Ⅲ, and 5 (10.2%) in stage Ⅳ. Age of the patients ranged from 33 to 76 years (Median 60 years). Pathologically, fourty six(94%) patients had squamous cell carcinoma, 2 (4% had adenocarcinoma, and 1 (2%) had adenosquamous cell carcinoma.
Overall response rate was 84%. 5-year survival rate was 49% for entire group (75% for stage Ib, 83% for Stage Ⅱa, 42.5% for stage Ⅱb, 25% for stage Ⅲ, 40% for stage Ⅳ).
Complications were observed in 11(22.4%) patients, who revealed rectal complications with most common frequency. Others were self limiting trifle ones such as wet desquamation, fatigue, mild leukopenia, etc.
The correlation of the survival rate with various factors (age, dose, Hb level, pelvic Iymph node status, performance status, local recurrence) was evaluated but showed no statistical significance except the age and local recurrence in this series; survival of patients less than 50 years of age was worse than that of the older, and the presence of local recurrence had worse prognosis(p< 0.05).
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KEYWORD
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Carcinoma of the uterine cervix, Curative radiotherapy, Intracavitary radiation, 5-year survival rate, Complications
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